SINGLE-DOSE THERAPY OF FALCIPARUM-MALARIA WITH MEFLOQUINE OR PYRIMETHAMINE-SULFADOXINE
- 1 January 1979
- journal article
- research article
- Vol. 57 (2) , 275-279
Abstract
A single oral dose (1.5 g) of mefloquine hydrochloride cured all of 37 patients with falciparum malaria and a single dose of pyrimethamine (75 mg) plus sulfadoxine (1.5 g) cured 34 of 38 patients. The rates at which parasitemia and fever abated were similar for the 2 regimens but mefloquine was associated with a higher incidence of gastrointestinal side effects.This publication has 3 references indexed in Scilit:
- Mefloquine (WR 142,490) in the Treatment of Human MalariaScience, 1975
- Treatment of Falciparum Malaria from Vietnam with a Phenanthrene Methanol (WR 33063) and a Quinoline Methanol (WR 30090)Antimicrobial Agents and Chemotherapy, 1973
- A review of the drug sensitivity of Plasmodium falciparum in Thailand.1972