Differential free fatty acid response to heparin in diabetics

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Abstract
Deleterious effects of elevated free fatty acids have been demonstrated in both diabetic and non-diabetic patients. Recent studies have shown drastic and prolonged elevations of free fatty acids following heparin injection in postoperative diabetic patients. This study demonstrated no significant difference in response of two groups of preoperative diabetics maintained on either insulin or oral hypoglycaemic agents, but it has revealed that individual diabetics who respond to heparin with a massive elevation of free fatty acids can be easily identified with a simple preoperative injection of 5000 units of intravenous heparin.

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