RNA Interference — A New Weapon against HIV and Beyond
- 24 October 2002
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 347 (17) , 1364-1367
- https://doi.org/10.1056/nejmcibr022294
Abstract
A recently discovered type of RNA, small interfering RNA, silences messenger RNA (the transcript of an active gene) by binding to specific sequences in the messenger RNA. Small interfering RNAs can block the replication of HIV in vitro by triggering the degradation of specific viral messenger RNAs. This work reveals new possibilities for controlling not only HIV infection but also the growth of cancer cells.Keywords
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