Chemoenzymatic synthesis of (+)-(4E,15E)-docosa-4,15-dien-1-yn-3-ol, a component of the marine sponge Cribrochalina vasculum
- 1 January 1996
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 10,p. 961-962
- https://doi.org/10.1039/p19960000961
Abstract
An acetylenic alcohol, (+)-(4E, 15E)-docosa-4,15-dien-1-yn-3-ol 1, isolated from the marine sponge Cribrochalina vasculum, was synthesized in highly enantiomerically pure form by lipase-catalysed transesterification with Novozym 435 (Candida antarctica).Keywords
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