Hepatic Hemangioendotheliosarcoma

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Abstract
Introduction Calamitous effects of new drugs have been emphasized in the current literature, with the withdrawal of many such as triparanol (MER-29) and etryptamine acetate (Monase). Fortunately only a few pregnant women were exposed to the mutilating effects on their offspring by thalidomide, but this was true only because the US Food and Drug Administration was adamant in considering the drug unsafe. Similarly the Council on Pharmacy and Chemistry of the American Medical Association in 19321 condemned the intravenous use of Thorotrast (thorium dioxide sol) for roentgen visualization of the liver and spleen because "the period of observation on patients and animals since its introduction was insufficient to rule out ensuing necrotic and/or malignant changes." The following case substantiates the wisdom of their judgment on a preparation initially benign but insidiously lethal. Report of Case A retired white prison guard, 65 years of age, was referred to the

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