HIGH-DOSE ETOPOSIDE IN THE TREATMENT OF RELAPSED PRIMARY BRAIN-TUMORS

  • 1 January 1985
    • journal article
    • research article
    • Vol. 69  (6) , 603-605
Abstract
Twenty-four patients with relapsed primary intracranial tumors were treated with high-dose etoposide (600-1000 mg/m2). All patients had received previous radiotherapy and 15 had had previous chemotherapy. The treatment was well-tolerated, with little toxicity. Only 1 patient showed a partial response, which was maintained for 78 wk. Four patients had stable disease, for a median of 15 wk. Etoposide failed to show useful activity in relapsed brain tumors.