Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis
Top Cited Papers
- 1 March 2008
- journal article
- research article
- Published by Elsevier in Molecular Cell
- Vol. 29 (5) , 541-551
- https://doi.org/10.1016/j.molcel.2007.12.023
Abstract
No abstract availableKeywords
This publication has 52 references indexed in Scilit:
- Role of Endoplasmic Reticulum Stress and c-Jun NH2-Terminal Kinase Pathways in Inflammation and Origin of Obesity and DiabetesDiabetes, 2005
- Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathwaysHuman Molecular Genetics, 2005
- Growing roles for the mTOR pathwayCurrent Opinion in Cell Biology, 2005
- Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2Genes & Development, 2005
- THE MAMMALIAN UNFOLDED PROTEIN RESPONSEAnnual Review of Biochemistry, 2005
- Phosphorylation and Functional Inactivation of TSC2 by Erk: Implications for Tuberous Sclerosisand Cancer PathogenesisPublished by Elsevier ,2005
- Increased Activation of the Mammalian Target of Rapamycin Pathway in Liver and Skeletal Muscle of Obese Rats: Possible Involvement in Obesity-Linked Insulin ResistanceEndocrinology, 2005
- Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR ComplexScience, 2005
- Ser/Thr Phosphorylation of IRS Proteins: A Molecular Basis for Insulin ResistanceScience's STKE, 2005
- Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1Science, 2000