Antibody-targeted thrombolytic agents.
- 1 January 1990
- journal article
- review article
- Published by Japanese Circulation Society in Japanese Circulation Journal
- Vol. 54 (4) , 345-353
- https://doi.org/10.1253/jcj.54.345
Abstract
Plasminogen activator therapy for acute myocardial infarction has become standard medical practice. Bleeding complications, however, limit the utility of the currently available agents. This article reviews how the tools of immunology, molecular biology and protein engineering are being used to develop safer and more effective plasminogen activators.Keywords
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