CALLA-positive myeloma: an aggressive subtype with poor survival.

  • 1 July 1985
    • journal article
    • case report
    • Vol. 66  (1) , 229-32
Abstract
Detailed immunotyping was carried out on 21 direct myeloma bone marrow aspirates and eight human myeloma cell lines. Four previously untreated common acute lymphoblastic leukemia antigen (CALLA)-positive myeloma patients were identified and six of eight cell lines (75%) were also positive. CALLA positivity, as part of an immature B phenotype, was found to correlate with very aggressive clinical disease: median survival six months v 56 months for the CALLA-negative group.

This publication has 0 references indexed in Scilit: