A New Synthesis of γ-Substituted α-Methylene-γ-butyrolactones (2-Methylene-4-alkanolides) using Catalysis by SnCI2/Amberlyst 15
- 1 January 1990
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1990 (06) , 530
- https://doi.org/10.1055/s-1990-26930
Abstract
Reaction of α-bromomethylacrylic acid with aldehydes or ketones in an SnCl2/amberlyst 15/THF/H2O system affords 2-methylene-4-alkanolides in mostly good yields.Keywords
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