Multivalent Neoglycoconjugates by Regiospecific Cycloaddition of Alkynes and Azides Using Organic-Soluble Copper Catalysts
Top Cited Papers
- 1 May 2003
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 5 (11) , 1951-1954
- https://doi.org/10.1021/ol034534r
Abstract
The construction of multivalent neoglycoconjugates is efficiently achieved by the regiospecific catalytic cycloaddition of alkynes and azides using the organic-soluble copper complexes (Ph3P)3·CuBr and (EtO)3P·CuI. The simultaneous use of microwave irradiation shortened notably the reaction times.Keywords
This publication has 30 references indexed in Scilit:
- Influencing Receptor−Ligand Binding Mechanisms with Multivalent Ligand ArchitectureJournal of the American Chemical Society, 2002
- Design and synthesis of glycodendrimersReviews in Molecular Biotechnology, 2002
- The Cluster Glycoside EffectChemical Reviews, 2002
- Chemical GlycobiologyScience, 2001
- Synthetic multivalent ligands in the exploration of cell-surface interactionsCurrent Opinion in Chemical Biology, 2000
- Synthetic receptorsJournal of the Chemical Society, Perkin Transactions 1, 2000
- Affinity enhancement by multivalent lectin–carbohydrate interactionGlycoconjugate Journal, 2000
- Recent developments in glycoconjugatesJournal of the Chemical Society, Perkin Transactions 1, 1999
- Polyvalente Wechselwirkungen in biologischen Systemen: Auswirkungen auf das Design und die Verwendung multivalenter Liganden und InhibitorenAngewandte Chemie, 1998
- Carbohydrate-Protein Interactions: Basis of GlycobiologyAccounts of Chemical Research, 1995