Association of IgG and IgM antibodies to phenolic glycolipid-l antigen ofMycobacterium lepraewith disease parameters in multibacillary leprosy patients

Abstract
IgG and IgM antibodies to the phenolic glycolipid-1 (PGL-1) antigen of Mycobacterium leprae were assessed using an enzyme-linked immunosorbent assay (ELISA) in 77 multibacillary leprosy patients. No correlations were found when their absorbance values were compared to: disease type and duration, bacillary load, reactional status, or concurrent secondary infection. A statistical difference was seen between patients with and without neurological deficiency.