Deletion of 3p25→pter in a primary follicular thyroid carcinoma and its metastasis
- 1 November 1993
- journal article
- Published by Wiley in Genes, Chromosomes and Cancer
- Vol. 8 (3) , 199-203
- https://doi.org/10.1002/gcc.2870080311
Abstract
We report the cytogenetic analysis of a follicular thyroid carcinoma and its bone metastasis. Both lesions had identical chromosomal abnormalities, with a der(3)t(2;3)(q13;p25) as the most likely primary clonal alteration. Our findings corroborate previous observations of frequent 3p deletions in thyroid follicular carcinomas and suggest that the minimal chromosomal region of loss in these tumors is 3p25→pter.Keywords
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