THE LINOLEIC ACID DEPRESSION (LAD) TEST FOR MULTIPLE SCLEROSIS USING the MACROPHAGE ELECTROPHORETIC MOBILITY (MEM) TEST

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Abstract
Using the MEM test of Field and Caspary, lymphocyte sensitization to thyroid antigen is demonstrable in all subjects: multiple sclerosis (MS) patients, those with other (destructive) neurological diseases (OND) and normals. The MEM-LAD test enables further differentiation of neurological patients. Linoleic acid inhibited the positive result by about 95% in MS, 58% in normals and 45% in OND. The high reduction appears to be a characteristic of MS. It is seen at all stages and in all forms of the disease, and is not materially influenced by moderate immunosuppressive therapy. The mothers of MS patients show an intermediate result of about 78%, suggesting a familial (genetic) background to the metabolic phenomenon discussed. There is evidence of an added exogenous factor for the development of the disease. The theoretical basis of the LAD test suggests further therapeutic trials of linoleic acid in treatment of MS.