The role of T-cell in inflammatory kidney disease
- 1 July 1995
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Nephrology and Hypertension
- Vol. 4 (4) , 354-358
- https://doi.org/10.1097/00041552-199507000-00012
Abstract
The fundamental role of cell-mediated immunity in inflammatory disease of the kidney has been established for some time. This review focusses on the recent advances in our understanding of the role of T-cells in the pathogenesis both of glomerulonephritis and interstitial nephritis. In particular, the increasing experimental evidence for a functional role for T-cells in promoting disease initiation and progression is examined. The ever increasing variety of T-cell-effector functions and their relevance are also discussed.Keywords
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