Cerebrospinal Fluid Penetration of Levofloxacin in Patients with Spontaneous Acute Bacterial Meningitis
Open Access
- 1 November 2001
- journal article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 33 (9) , e109-e111
- https://doi.org/10.1086/323406
Abstract
We have assessed levofloxacin penetration in cerebrospinal fluid (CSF) and the liquor-to-plasma ratio (CL/CP) at 2 hours after dosing in 5 patients with spontaneous acute bacterial meningitis. CSF levofloxacin concentration at 2 hours after dosing was 1.99 ± 0.67 μg/mL, and the CL/CP at 2 hours after dosing was 0.34 ± 0.09.Keywords
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