Prostaglandins in experimental otitis media

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Abstract
Levels of prostaglandins in serum, plasma and middle ear effusions (MEE) in chinchilla were measured by radioimmunoassay. Higher levels of PGE2 and PGF2α were observed in the POM group than in the SOM group. Prostaglandins appear to play important roles as a mediator of the inflammatory response in experimentally induced purulent otitis media. Die Prostaglandinwerte im Serum, Plasma und Mittelohrerguß werden beim Chinchilla mittels Radioimmuntest bestimmt. Es zeigt sich, daß Prostaglandine wahrscheinlich eine wichtige Mittlerrolle bei Entstehung einer experimentellen eitrigen Mittelohrentzündung spielen.