Autonomic Responses in Prefrontal Leucotomy

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Abstract
In bilateral prefrontal leucotomy inter alia the fronto-subthalamic, the fronto septal and fronto-hypothalamic (posterior) projections may be severed, together with reciprocally projecting tracts. These may represent the anatomical basis for the altered autonomic visceral disturbances observed following operations. The reports on bilateral leucotomy emphasize the post-operative “improvement in autonomic functions with a tendency to gain weight” (Vonderahe). After lobotomy transient visceral disturbances make their appearance, such as disturbed sphincter control and slightly but permanently decreased blood pressure, whilst vasomotor disturbances and sweating on the contralateral half of the body have been noted following unilateral lobotomy.

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