Reduced antibody-dependent cell-mediated cytotoxicity in systemic lupus erythematosus.

  • 1 May 1975
    • journal article
    • Vol. 20  (2) , 187-92
Abstract
The peripheral blood mononuclear cells from twenty-three patients with SLE were studied. They showed a reduction in antibody-dependent cell-mediated cytotoxicity. This reduction was significantly related to disease activity. No correlations were found with other clinical features. Some of the possible explanations for this finding are discussed.