Choline Acetyltransferas

Abstract
The central role played by acetylcholine in the conduction of the nerve impulse is now generally accepted after decades of controversy. It is assumed that acetylcholine acts as a trigger, inducing changes in the cation permeability of electrically excitable membranes through attachment to a receptor biopolymer. While an enormous amount of scientific work has been centered on the receptor proteins to which acetylcholine is attached and on the enzyme (acetylcholinesterase) responsible for the hydrolysis of acetylcholine, much less effort has been centered on studying the synthesis and the regulation of the synthesis of this molecule.