Choline Acetyltransferas
- 1 January 1977
- journal article
- research article
- Published by Taylor & Francis in CRC Critical Reviews in Biochemistry
- Vol. 4 (4) , 341-370
- https://doi.org/10.3109/10409237709105460
Abstract
The central role played by acetylcholine in the conduction of the nerve impulse is now generally accepted after decades of controversy. It is assumed that acetylcholine acts as a trigger, inducing changes in the cation permeability of electrically excitable membranes through attachment to a receptor biopolymer. While an enormous amount of scientific work has been centered on the receptor proteins to which acetylcholine is attached and on the enzyme (acetylcholinesterase) responsible for the hydrolysis of acetylcholine, much less effort has been centered on studying the synthesis and the regulation of the synthesis of this molecule.Keywords
This publication has 94 references indexed in Scilit:
- Interaction of analogs of coenzyme A with choline acetyltransferaseBiochemistry, 1977
- Evidence for a thiol reagent inhibiting choline acetyltransferase by reacting with the thiol group of coenzyme a forming a potent inhibitorBiochemical and Biophysical Research Communications, 1976
- Antibody production to choline acetyltransferase purified from human brainLife Sciences, 1974
- Inactivation of choline acetyltransferases by an antiserum to the enzyme from mouse brainLife Sciences, 1974
- Inhibition of choline acetylase from the house fly (musca domestica l.) and mouseLife Sciences, 1971
- Halogen substituted derivatives of acetylcholine as inhibitors of choline acetyltransferaseLife Sciences, 1969
- A Coenzyme A analogue, Desulpho-CoA; Preparation and effects on various enzymesBiochemical and Biophysical Research Communications, 1966
- Physical and Chemical Effects of Substituent Groups on Multiple Bonds. II. Thiolesters1Journal of the American Chemical Society, 1960
- Studies on Model Compounds for Coenzyme A. A Kinetic Study of Aminolysis and Hydrolysis of Ethyl Thioacetate and β-Acetaminoethyl Thioacetate in Aqueous SolutionJournal of the American Chemical Society, 1953
- The Absorption and Re-emission of Light by cis- and trans-Stilbenes and the Efficiency of their Photochemical IsomerizationJournal of the American Chemical Society, 1940