Insecticidal Activity of Spider (Araneae), Centipede (Chilopoda), Scorpion (Scorpionida), and Snake (Serpentes) Venoms

Abstract
Venoms from 59 spider species were injected into Manduca sexta (L.) larvae to assess inherent insecticidal activity. Venom potency varied widely, but was relatively weak for many large spiders such as wolf (Lycosidae), tarantulas (Theraphosidae), lynx (Oxyopidae), and orb weavers (Araneidae). Potent insecticidal venoms occur in medically important species such as black widow ( Latrodectus ) and Loxosceles as well as ground spiders (Gnaphosidae) and certain primitive hunters. Compared with spider venoms, snake and scorpion venoms are weaker, whereas centipede venom is quite active against M. sexta. None of these venoms are active orally, but several spider venoms are toxic topically at greatly exaggerated levels. Diabrotica undecimpunctata undecimpunctata Mannerheim larvae are much less sensitive to these venoms than M. sexta .

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