Abstract
Some of the difficulties associated with the problem of determining drug effects on the visual sensory system are outlined. Specific consideration is given to the selection of human and animal subjects for study, the use of electrophysiological techniques, and a variety of experimental procedures which may be employed. Problems associated with the attention and motivation of subjects, the use of anesthesia, and the need for investigation of a wide range of drug dosages are discussed. Some experiments which reveal fairly specific effects on visual function are described.

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