Selective binding and sensing of guanidinium ions by lipophilic cyclodextrins

Abstract
Potentiometric sensors based on lipophilic alkylated cyclodextrins exhibit a good response to the guanidinium ion, with higher selectivity over sodium than previously reported ionophores; 2,6-didodecyl-β-cyclodextrin has also been shown to exhibit selective response to the guanidine derivatives metformin and phenformin in a simulated clinical electrolyte background.

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