PREGNANDIOL EXCRETION IN FEMALE PSEUDOHERMAPHRODITISM

Publisher Website
Google Scholar
Abstract
The end product of progesterone metabolism, pregnandiol, is determined as sodium pregnandiol glucuronidate by a gravimetric method developed by Venning and Browne.1 Estimations of this complex have been made by various investigators in normal and pathologic menstrual periods, in normal pregnancy, abortions, toxemias and, lastly, in cases of the adrenogenital syndrome.2Except in an isolated case (a child aged 3 years), there have been no data available among children.3 The accumulated literature to date has already been well summarized, but it may be well to recall a few pertinent facts regarding the excretion of pregnandiol. This compound is excreted in the urine during the luteal phase of the normal menstrual cycle when the corpus luteum is active and absent during the first half of the intermenstrual phase. The amount of pregnandiol determined for the whole cycle may vary from 34 to 54 mg., although the daily output

This publication has 0 references indexed in Scilit: