Interaction of Oligodeoxyribonucleotides Through Formation of Chimeric Duplex/Triplex Complexes
- 1 May 1994
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 13 (4) , 997-1005
- https://doi.org/10.1080/15257779408011872
Abstract
An intramolecular duplex/triplex chimera is formed between d-CTTCCT-(T)4-TCCTTCAGCACA and target d-GTT TGTGCTGAAGGA CACAC. The high Tm and hypochromicity of the triplex part of the chimera may be due to additional interactions outside the underlined binding site of the 20-mer.Keywords
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