Thyroid Transcription Factor-1 is a Marker of Lung and Thyroid Carcinomas
- 1 March 2000
- journal article
- review article
- Published by Wolters Kluwer Health in Advances in Anatomic Pathology
- Vol. 7 (2) , 123-127
- https://doi.org/10.1097/00125480-200007020-00007
Abstract
Thyroid transcription factor-1 (TTF-1) is a tissue specific transcription factor expressed in epithelial cells of the thyroid and lung, as well as in certain areas of the brain. Recent investigations have shown that TTF-1 is also commonly present in a wide variety of thyroid and lung tumors. Because of its restrictive expression, TTF-1 is a useful immunohistochemical marker in the diagnosis of tumors of thyroid or lung origin.Keywords
This publication has 0 references indexed in Scilit: