Induction of mutations in the zebrafish with ultraviolet light
- 14 April 1992
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 59 (2) , 93-101
- https://doi.org/10.1017/s0016672300030305
Abstract
Summary: Recessive lethal germline and specific locus somatic mutations were induced efficiently in the zebrafish by exposure of mature sperm to UV light. Mutagenesis of sperm yielded mosaic individuals: clones bearing novel mutations represented approximately 12–25% of the haploid germ cells and 25–50 % of the somatic tissue. Simple methods are described for the reliable identification and propagation of newly arising developmental mutations in zebrafish.Keywords
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