Roles of taste and post-ingestional factors in the satiation of sodium appetite in rats.

Abstract
Twenty-four adrenalectomized rats, 9-hr. NaCl deprived, were used to study effects of oral ingestion and stomach loading of NaCl solutions on satiation of NaCl appetite, when Ss [subjects] drank 10 ml. of .4 M NaCl, they drank significantly less NaCl in a test administered 2 hr. later than when they had been stomach tubed with 10 ml. of .4 M NaCl or than when they had drunk 10 ml. of .3 M sucrose. Stomach loading of NaCl was no more effective than stomach loading of H2O and only slightly more effective than stomach loading of sucrose in reducing NaCl appetite, even though the stomach loading of NaCl was sufficient to result in normal blood plasma sodium concentrations.

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