Ointment-based mechlorethamine treatment for mycosis fungoides
- 15 December 1983
- Vol. 52 (12) , 2214-2219
- https://doi.org/10.1002/1097-0142(19831215)52:12<2214::aid-cncr2820521207>3.0.co;2-h
Abstract
The treatment of skin disease with topical mechlorethamine has been restricted because of the frequent development of contact dermatitis. A series of 43 patients with mycosis fungoides in Stages 1A (17), IB (22), II (2), and III (2) were treated with an ointment-based mechlorethamine, prepared by an anhydrous method. Complete clearing occurred in 26 patients over a 42-month evaluation period. The incidence of contact dermatitis was very low. Only 1 of 31 patients exposed to mechlorethamine for the first time, and only 3 of 12 patients with a history of previous hypersensitivity to mechlorethamine, developed contact dermatitis to the ointment-based mechlorethamine. Cancer 52:22140-2219, 1983.This publication has 26 references indexed in Scilit:
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