Transmethylation of Phosphatidylethanolamine: An Initial Event in Embryonic Chicken Lens Fiber Cell Differentiation
- 24 September 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 217 (4566) , 1265-1267
- https://doi.org/10.1126/science.7112130
Abstract
Agents that induce differentiation of lens epithelial cells into lens fiber cells in vitro transiently stimulate the transmethylation of phosphatidylethanolamine. Inhibition of transmethylation by 3-deazaadenosine results in a corresponding inhibition of the cell elongation that characterizes lens fiber formation, suggesting that phospholipid methylation plays an essential role in the differentiation of these cells.This publication has 25 references indexed in Scilit:
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