Four dominant autosomal mutations affecting skin and hair development in the mouse

Publisher Website
Google Scholar
Abstract
Four new dominant autosornal mutations influencing the development of skin and hair in the mouse were tested for allellsm with each other and with hairless, hr. Three of the mutations probably constitute an allelic series and have been given the symbols Frla Frlb, and Frlc. The Fri series shows no evidence of linkage with hr. The fourth mutation, Hrn is a dominant and homozygous viable allele at the hr locus. With the possible exception of Fr1b, all mutants were of spontaneous origin. Because of their unique characteristics, these new mutants are of potential value as mouse model systems in studies of skin carcinogenesis and related areas of research.

This publication has 1 reference indexed in Scilit: