Studies on Equine Immunoglobulins
Open Access
- 1 November 1970
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 105 (5) , 1253-1263
- https://doi.org/10.4049/jimmunol.105.5.1253
Abstract
A comparative antigenic analysis of horse IgG, IgG(T) and γ1-component was carried out by immunodiffusion. In addition to sharing antigenic determinants in common with the L chain and Fab fragment of IgG, IgG(T) and γ1-component each share a similar set of antigenic determinants in common with the Fc fragment of horse IgG. γ1-Component can be further shown, however, to share an additional set of antigenic determinants in common with the Fc fragment of IgG-globulin which is absent from IgG(T). Based on the immunologic data, schematic models for the antigenic structures of horse IgG, IgG(T) and γ1-component are proposed.Keywords
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