UTERINE AND OVARIAN RESPONSE TO PARTIAL AND SUBTOTAL OVARIAN RESECTION1

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Abstract
In 4 rhesus monkeys 1 ovary was removed, and at intervals thereafter the 2d was reduced by excising half the remaining tissue in 3 successive operations. Occurrence of ovulation, character of menstrual cycles and size of uterus were followed throughout 2 yrs. 121/2% of the total amt. of ovarian tissue sustained menstrual cycles normal in length and type of bleeding. Frequent ovulation took place in the ovarian fragments and palpation indicated that the uterus in each animal was normal in size. Further reduction of ovarian tissue to 61/4% was followed by regular cycles, and ovulation in 2 instances. The endometrium of each uterus was essentially normal for the particular phase of the cycle at removal. Hypertrophy, as suggested by the sum of the wts. of the parts of the 2d ovary to the whole of the ovary, appeared on histological examination to be largely due to the necessary inclusion of the degenerating follicles and corpora lutea. In one animal accessory ovarian tissue was found in the broad ligament.

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