IgE-Induced Changes in Human Basophil Cyclic AMP Levels
- 1 January 1978
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 56 (5) , 473-478
- https://doi.org/10.1159/000232059
Abstract
We studied a unique patient with 77% basophils, not different from normal by a number of criteria, in order to measure the changes in cyclic AMP level associated with IgE-mediated histamine release. In accordance with previous hypothesis and circumstantial evidence, anti-IgE challenge led to a significant fall in the cyclic AMP level which preceded histamine release.Keywords
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- Measurement of IgE on Human Basophils: Relation to Serum IgE and Anti-IgE-Induced Histamine ReleaseThe Journal of Immunology, 1977
- INHIBITION OF MAST-CELL DEGRANULATION BY ANTI-NFLAMMATORY AGENTS1967