Developmental Potential of Somatic Nuclei Transplanted into Meiotic Oocytes of Rana pipiens
- 25 July 1980
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 209 (4455) , 517-519
- https://doi.org/10.1126/science.6967227
Abstract
Somatic nuclei, when transplanted into oocytes at the stage of first meiotic metaphase, were induced to undergo chromosome condensation and alignment on spindles. When the oocytes completed maturity in vitro and were activated, the somatic nuclei transformed into "fertilization" nuclei and promoted development through embryogenesis. Thus somatic nuclei can reversibly respond to cytoplasms directing either meiotic or mitotic events, and somatic nuclei from differentiated cells may be reversed by conditioning in oocytes.Keywords
This publication has 3 references indexed in Scilit:
- The Current Status of Cloning and Nuclear Reprograming in Amphibian EggsPublished by Springer Nature ,1980
- Oocyte MaturationPublished by Elsevier ,1979
- Transplantations of blastula nuclei into activated eggs from the body cavity and from the uterus of Rana pipiensDevelopmental Biology, 1961