Independent Control of Replication Initiation of the Two Vibrio cholerae Chromosomes by DnaA and RctB
- 1 September 2006
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 188 (17) , 6419-6424
- https://doi.org/10.1128/jb.00565-06
Abstract
Although the two Vibrio cholerae chromosomes initiate replication in a coordinated fashion, we show here that each chromosome appears to have a specific replication initiator. DnaA overproduction promoted overinitiation of chromosome I and not chromosome II. In contrast, overproduction of RctB, a protein that binds to the origin of replication of chromosome II, promoted overinitiation of chromosome II and not chromosome I.Keywords
This publication has 28 references indexed in Scilit:
- Autorepression of RctB, an Initiator of Vibrio cholerae Chromosome II ReplicationJournal of Bacteriology, 2006
- Multipartite Regulation ofrctB, the Replication Initiator Gene ofVibrio choleraeChromosome IIJournal of Bacteriology, 2005
- MicroReview: Divided genomes: negotiating the cell cycle in prokaryotes with multiple chromosomesMolecular Microbiology, 2005
- Vibrios Commonly Possess Two ChromosomesJournal of Bacteriology, 2005
- Distinct segregation dynamics of the two Vibrio cholerae chromosomesMolecular Microbiology, 2004
- Distinct Replication Requirements for the Two Vibrio cholerae ChromosomesCell, 2003
- Escherichia coliCells with Increased Levels of DnaA and Deficient in Recombinational Repair Have Decreased ViabilityJournal of Bacteriology, 2003
- The bacterial replication initiator DnaA. DnaA andoriC, the bacterial mode to initiate DNA replicationFEMS Microbiology Reviews, 2002
- Genomic complexity and plasticity ofBurkholderia cepaciaFEMS Microbiology Letters, 1996
- The DnaA protein determines the initiation mass of Escherichia coli K-12Cell, 1989