Clearance of Bacteria by the Lower Respiratory Tract
- 20 December 1963
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 142 (3599) , 1572-1573
- https://doi.org/10.1126/science.142.3599.1572
Abstract
The disappearance of inhaled bacteria from the lungs of mice is rapid and predictable over an 8-hour period following pulmonary implantation by an aerosol. This indicates that important clearance mechanisms are active in the bronchopulmonary tree. The constant pattern of clearance offers an experimental system in which the effects of various conditions relevant to respiratory infection can be estimated quantitatively. Herein, the effects of hypoxia, alcohol, cigarette smoke, and cortisone are described.Keywords
This publication has 2 references indexed in Scilit:
- Bacteriologic Flora of the Lower Respiratory TractNew England Journal of Medicine, 1961
- PHAGOCYTOSIS OF FOREIGN MATERIAL IN THE LUNGPhysiological Reviews, 1941