Rapid Serogroup Switching inNeisseria meningitidis
- 20 January 2000
- journal article
- letter
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 342 (3) , 219-220
- https://doi.org/10.1056/nejm200001203420319
Abstract
In Neisseria meningitidis, the horizontal transfer of siaD genes encoding polysialyltransferases has been shown to result in capsular serogroup switching in vitro.1 The presence of closely related clones with different serogroups suggests that serogroup switching also occurs in vivo.2,3 However, the time course of the transfer of siaD genes in humans is unknown.Keywords
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