A double-blind trial of idoxuridine in recurrent genital herpes
- 1 January 1977
- journal article
- clinical trial
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 3 (suppl A) , 131-137
- https://doi.org/10.1093/jac/3.suppl_a.131
Abstract
Fifty-three patients with recurrent genital herpes were subjected to a double-blind trial with topically applied idoxuridine in dimethyl suiphoxide and dimethyl suiphoxide alone as control. Lesions treated with 20% idoxuridine healed more rapidly and shed virus for a shorter period than those treated with 5% idoxuridine or the controls. Five per cent idoxuridine however was superior to the control. Thirty-four of the patients were followed up for periods up to 2 years but no significant difference in the recurrence rate of the lesions was observed between those treated with idoxuridine and the controls.Keywords
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