RECURRENCE OF VULVOVAGINAL CANDIDOSIS DURING PREGNANCY - COMPARISON OF MICONAZOLE VS NYSTATIN TREATMENT

  • 1 January 1976
    • journal article
    • research article
    • Vol. 48  (4) , 491-494
Abstract
The efficacy of miconazole and nystatin in the treatment of vulvovaginal candidosis was compared in a multicenter trial involving 94 pregnant patients. All patients had subjective complaints and were mycologically positive. Miconazole 2% vaginal cream was applied once daily for at least 10 days by 45 patients; the 49 others received nystatin tablets for intravaginal application during 7-9 days. At the 1st examination following treatment, the cure rate with miconazole was 83% and with nystatin 68%. Follow-up examinations revealed a significantly lower recurrence rate in the miconazole-treated group. No important adverse experiences were noted.

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