A possible genetic component of obesity in childhood. Observations on acid phosphatase polymorphism
- 1 January 1990
- journal article
- research article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 46 (1) , 90-91
- https://doi.org/10.1007/bf01955426
Abstract
Phenotypes of acid phosphatase with low enzymatic activity (ACP1 A and BA) are correlated with the highest degree of body mass increase observed in a sample of obese children. Since acid phosphatase probably functions as a flavin-mononucleotide phosphatase, differential modulation of flavo-enzyme activity and energy metabolism due to acid phosphatase genetic variability may explain the observed association.This publication has 12 references indexed in Scilit:
- Foetal macrosomia and erythrocyte acid phosphatase (ACP1) polymorphism in diabetic and normal pregnancyEarly Human Development, 1988
- Foetal macrosomia and erythrocyte acid phosphatase (ACP1) polymorphism in diabetic and normal pregnancy.1988
- Phenotypic variation in the phosphotransferase activity of human red cell acid phosphatase (ACP1)Human Genetics, 1986
- An Adoption Study of Human ObesityNew England Journal of Medicine, 1986
- ACP1GUA-1 - A LOW-ACTIVITY VARIANT OF HUMAN-ERYTHROCYTE ACID-PHOSPHATASE - ASSOCIATION WITH INCREASED GLUTATHIONE-REDUCTASE ACTIVITY1982
- Is obesity a genetic disease?1982
- PREDISPOSITION TO OBESITYThe Lancet, 1980
- Activity of the ‘red cell’ acid phosphatase locus in other tissuesAnnals of Human Genetics, 1973
- Some notes on the geographical distribution of the human red cell acid phosphatase phenotypesHuman Genetics, 1972
- Red Cell Acid Phosphatase Variants: A New Human PolymorphismNature, 1963