Inhibitors paradoxically prime kinases

This publication has 12 references indexed in Scilit:

• Inhibitor hijacking of Akt activation
  Nature Chemical Biology, 2009
• PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity
  Nature Structural & Molecular Biology, 2009
• A quantitative analysis of kinase inhibitor selectivity
  Nature Biotechnology, 2008
• Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition
  Oncogene, 2007
• Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  The Journal of Pharmacology and Experimental Therapeutics, 2007
• Rational design of inhibitors that bind to inactive kinase conformations
  Nature Chemical Biology, 2006
• Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo
  Molecular Cancer Therapeutics, 2005
• A Unique Structure for Epidermal Growth Factor Receptor Bound to GW572016 (Lapatinib)
  Cancer Research, 2004
• A chemical switch for inhibitor-sensitive alleles of any protein kinase
  Nature, 2000
• The hydrophobic phosphorylation motif of conventional protein kinase C is regulated by autophosphorylation
  Current Biology, 1999