The Relationship Between Cyclooxygenase-2 Expression and Colorectal Cancer
Open Access
- 6 October 1999
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 282 (13) , 1254-1257
- https://doi.org/10.1001/jama.282.13.1254
Abstract
Colorectal cancer is the third most common cancer in both men and women in most Western countries, although incidence and mortality rates are decreasing in the United States.1 Numerous studies have shown that the level of spread through the bowel wall and adjacent lymph node involvement are primary predictors of long-term outcome in patients with colorectal cancer.2 Other features known to be related to survival include vascular and perineural invasion, tumor necrosis, character of invasive margin, and differentiation.3Keywords
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