Combination Effect of Piperacillin with Four Aminoglycosides on Nonfermenting Gram-Negative Bacteria
- 1 January 1981
- journal article
- research article
- Published by S. Karger AG in Chemotherapy
- Vol. 27 (1) , 39-43
- https://doi.org/10.1159/000237953
Abstract
The in vitro efficacy of piperacillin in combination with gentamicin, tobramycin, amikacin and netilmicin against 57 nonfermenting gram-negative bacterial strains was compared by use of the checkerboard agar dilution technique. On average 34% of all nonfermenting strains were inhibited by additive, 13% by synergistic piperacillin-aminoglycoside combinations. Great variation occurred between the different bacterial species. Piperacillin-aminoglycoside combinations were most active on Pseudomonas aeruginosa and least potent on Pseudomonas cepacia. Piperacillin was highly active against P. aeruginosa, P. cepacia, Pseudomonas fluorescens-putida and Acinetobacter species.This publication has 10 references indexed in Scilit:
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