Synthetic Approach Toward Antibiotic Tunicamycins - VII Synthesis of Tunicamine and Tunicaminyl Uracil Derivative
- 1 March 1985
- journal article
- research article
- Published by Taylor & Francis in Journal of Carbohydrate Chemistry
- Vol. 4 (1) , 99-112
- https://doi.org/10.1080/07328308508062952
Abstract
A higher carbon carbohydrate moiety of antibiotic tunica-mycins named tunicamine has been synthesized in a protected form. The key reaction step of the synthesis is a potassium fluoride catalyzed Henry reaction of a 5-nitroribose derivative and a dial do-galactosamine derivative. The tunicamine derivative has been converted to a tunicaminyl uracil derivative by condenation with bis(trimethylsilyl) uracil.This publication has 9 references indexed in Scilit:
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