DNA topoisomerases as targets for anticancer drugs
Open Access
- 1 December 2001
- journal article
- research article
- Published by Hindawi Limited in Journal of Clinical Pharmacy & Therapeutics
- Vol. 26 (6) , 405-416
- https://doi.org/10.1046/j.1365-2710.2001.00368.x
Abstract
DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth. Over...Keywords
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