Platelet-Function Tests: Predictive Value

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Abstract
There is now available a bewildering array of platelet-function studies to further bedevil the many clinicians who struggle to understand hemostasis and thrombosis. Platelet aggregation, glass-bead retention, determination of 14C-serotonin release, assay of von Willebrand-factor activity, platelet-factor-3 availability measurements and other technics allow accurate classification of qualitative platelet defects, and have improved our understanding of the pathophysiology of hemostasis. Unfortunately, however, none of these tests correlate well with the clinical importance of platelet disorders. Only the template bleeding time seems to predict the likelihood of excessive bleeding.A pathologic extension of the platelet's role in hemostasis is its role in . . .

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