Anti‐Lea as an Autoantibody in the Serum of a Le (a – b+) Individual
- 8 July 1978
- journal article
- research article
- Published by Wiley in Transfusion
- Vol. 18 (4) , 436-440
- https://doi.org/10.1046/j.1537-2995.1978.18478251237.x
Abstract
The first example of anti‐Lea, as an autoantibody, in the serum of a phenotypically Le (a–b+) individual is described. The patient is a 55 year old male with squamous cell carcinoma of the esophagus. His saliva contains Lea, Leb and H substances, and inhibits the hemagglutinating activity of his serum anti‐Lea. The Leb antigen content of his red blood cells is approximately half that of control Le (a–b+) red blood cells. The patient's disease process may be responsible for the development of this unexpected autoantibody.This publication has 9 references indexed in Scilit:
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