MICRO-GLANDULAR HYPERPLASIA IN VAGINAL ADENOSIS ASSOCIATED WITH ORAL-CONTRACEPTIVES AND PRENATAL DIETHYLSTILBESTROL EXPOSURE

  • 1 January 1977
    • journal article
    • research article
    • Vol. 49  (4) , 430-434
Abstract
Cases (8) of microglandular hyperplasia arising in vaginal adenosis are presented. Five patients had taken oral contraceptives and a 6th was pregnant at the time the lesion was discovered; a history of prenatal exposure to diethylstilbestrol (DES) was present in 5 cases. It is important to differentiate microglandular hyperplasia, which is benign, from clear cell adenocarcinoma, which arises in a background of vaginal adenosis.

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