Malignant Thymoma with Metastases in a Dog

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Abstract
An 8-year-old male Wire-Haired Fox Terrier with respiratory distress and cough had a malignant thymoma that had metastasised to the lungs, spleen, liver, diaphragm, bronchial and mediastinal nodes, and pericardium by transcoelomic, vascular, and lymphatic routes. Myasthenia gravis, which occurs in some human patients with thymoma, was not evident. There are few reports of true thymomas in dogs [5]. Talerman and Gwynn [6] described one case and in a review of the literature found only five cases. Watson and Farrow [8] and Hall et al. [2] have since reported one case each. All the reported thymomas were benign with no evidence of metastasis. A case of a malignant thymoma in a dog in which there was infiltration of tissue with transcoelomic and embolic spread is described.

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